Effects of anodal polarization on protein kinase Cγ (PKCγ) in the rat brain.

  title={Effects of anodal polarization on protein kinase Cγ (PKCγ) in the rat brain.},
  author={Nazrul Islam and M Aftabuddin and Akiyoshi Moriwaki and Yuichi Hori},
  journal={Indian journal of physiology and pharmacology},
  volume={41 3},
An anodal direct current of 0.3 microA or 30.0 microA was unilaterally applied for 30 min or 3 hr to the surface of the sensorimotor cortex of rats, and the effects of anodal polarization on protein kinase C (PKCgamma) activity were examined. The brains were processed by means of immunocytochemistry using the monoclonal antibody 36G9 raised against purified PKCgamma. In sham-operated animals, PKCgamma-like-immunoreactivity (PKCgamma LI) was noted in neuronal cytoplasm, as well as in processes… CONTINUE READING


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