Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.

@article{Mendes2004EffectsOA,
  title={Effects of androgen manipulation on alpha1-adrenoceptor subtypes in the rat seminal vesicle.},
  author={F{\'u}lvio Rieli Mendes and Margarete Hamamura and Daniel B C Queir{\'o}z and Catarina Segreti Porto and Maria Christina Werneck de Avellar},
  journal={Life sciences},
  year={2004},
  volume={75 12},
  pages={1449-63}
}
This study analyses possible changes during surgical and chemical castration in the expression and pharmacological characteristics of alpha1-adrenoceptor in adult rat seminal vesicle. Ribonuclease protection assays indicated that alpha1a--was the predominant mRNA, while alpha1b-and alpha1d-adrenoceptor transcripts were detected in lower abundance in this tissue. alpha1a-adrenoceptor mRNA expression presented a complex dependency on androgens, while alpha1b- and alpha1d-adrenoceptor transcripts… CONTINUE READING
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