Effects of anaesthetic agents on basal and histamine-stimulated acid secretion in the fistula rat.


OBJECTIVES Anaesthetized rats or surgically modified preparations such as the Shay rat are widely used to study upper gastrointestinal function in the laboratory. Despite the existence of reports demonstrating that agents such as barbiturates can influence acid output, a systematic study of the effects of anaesthetics on gastric secretion has not been… (More)


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