Effects of an overnight intravenous lipid infusion on intramyocellular lipid content and insulin sensitivity in African-American versus Caucasian adolescents.

@article{Lee2013EffectsOA,
  title={Effects of an overnight intravenous lipid infusion on intramyocellular lipid content and insulin sensitivity in African-American versus Caucasian adolescents.},
  author={Sojung Lee and Christoph Hans Boesch and Jennifer L Kuk and Silva Arslanian},
  journal={Metabolism: clinical and experimental},
  year={2013},
  volume={62 3},
  pages={
          417-23
        }
}
OBJECTIVE To explain the predisposition for insulin resistance among African American (AA) adolescents, this study aimed to: 1) examine changes in intramyocellular lipid content (IMCL), and insulin sensitivity with intralipid (IL) infusion; and 2) determine whether the increase in IMCL is comparable between AA and Caucasian adolescents. MATERIALS AND METHODS Thirteen AA and 15 Caucasian normal-weight adolescents (BMI <85th) underwent a 3-h hyperinsulinemic-euglycemic clamp, on two occasions… CONTINUE READING
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