Effects of an enteric anaerobic bacterial culture supernatant and deoxycholate on intestinal calcium absorption and disaccharidase activity.

@article{Walshe1990EffectsOA,
  title={Effects of an enteric anaerobic bacterial culture supernatant and deoxycholate on intestinal calcium absorption and disaccharidase activity.},
  author={Karen Walshe and M J R Healy and Anthony B J Speekenbrink and Conor T. Keane and Donald George Weir and Rory O'Moore},
  journal={Gut},
  year={1990},
  volume={31 7},
  pages={770-6}
}
Fifty two strains of anaerobic bacteria isolated from the upper gut of patients with small intestinal bacterial overgrowth were screened for phospholipase activity. Bacteroides melaninogenicus spp intermedius had the greatest activity. The effects of culture supernatants of this organism and deoxycholate on intestinal calcium absorption and disaccharidase activity were studied using a rat closed loop model. The supernatant decreased the in vitro uptake of calcium by 15% (p less than 0.001… CONTINUE READING