Effects of an antimitotic drug on mechanical behaviours of the cytoskeleton in distinct grades of colon cancer cells.

@article{Seyedpour2015EffectsOA,
  title={Effects of an antimitotic drug on mechanical behaviours of the cytoskeleton in distinct grades of colon cancer cells.},
  author={Seyed Mohsen Seyedpour and Mohammad Pachenari and Mohsen Janmaleki and Mansour Alizadeh and Hossein Hosseinkhani},
  journal={Journal of biomechanics},
  year={2015},
  volume={48 6},
  pages={1172-8}
}
Biomechanical behaviours of cells change during cancer progression due to alterations in the main cytoskeletal proteins. Microtubules play a vital role in mitosis and in supporting the integrity of the cell due to their ability to withstand high compressive loads. Accordingly, microtubule-targeting agents (MTAs) have become one of the most promising classes… CONTINUE READING