Differential effects of amyloid-beta 1-40 and 1-42 fibrils on 5-HT1A serotonin receptors in rat brain.
- Mathieu Verdurand, Fabien Chauveau, +5 authors Luc Zimmer
- Neurobiology of aging
- 2016
9 Excerpts
Effects of amyloid-β peptides on the serotoninergic 5-HT1A receptors in the rat hippocampus.
- Published 2011 in Neurobiology of aging
Abstract
A recent [(18)F]MPPF-positron emission tomography study has highlighted an overexpression of 5-HT(1A) receptors in the hippocampus of patients with mild cognitive impairment compared to a decrease in those with Alzheimer's disease (AD) [Truchot, L., Costes, S.N., Zimmer, L., Laurent, B., Le Bars, D., Thomas-Antérion, C., Croisile, B., Mercier, B., Hermier… (More)