Effects of amphetamine on the turnover rate of brain catecholamines and motor activity.

@article{Costa1972EffectsOA,
  title={Effects of amphetamine on the turnover rate of brain catecholamines and motor activity.},
  author={Erminio Costa and Antonio Groppetti and M. Kabir Naimzada},
  journal={British journal of pharmacology},
  year={1972},
  volume={44 4},
  pages={
          742-51
        }
}
1. Rats receiving (+)-amphetamine (either 0.3 or 0.2 mg/kg, i.v.) are anorexic. Only the former dose increases their motor activity. Both doses fail to change dopamine (DM) and noradrenaline (NA) concentrations in striatum and teldiencephalon. The turnover rate of striatal DM is increased only by 0.3 mg/kg of (+)-amphetamine; neither dose changes NA turnover rate in teldiencephalon.2. (-)-Amphetamine (1 mg/kg, i.v.) causes anorexia and hyperthermia in rats but it changes neither the steady… CONTINUE READING
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