Effects of amphetamine and haloperidol on avoidance behavior and exploratory activity.

@article{Kovcs1978EffectsOA,
  title={Effects of amphetamine and haloperidol on avoidance behavior and exploratory activity.},
  author={G{\'a}bor L{\'a}szl{\'o} Kov{\'a}cs and D de Wied},
  journal={European journal of pharmacology},
  year={1978},
  volume={53 1},
  pages={103-7}
}
The effect of graded doses of D-amphetamine and haloperidol were tested on retention of a one trial learning passive avoidance response, on extinction of pole-jumping active avoidance behavior and on open-field activity. Low doses of amphetamine (10 microgram/animal) increased passive avoidance latency when given s.c. 1 h prior to the retention test. Higher doses (20 and 1000 microgram/animal) caused a bimodal distribution of avoidance latencies. Haloperidol (0.03 or 1.0 microgram/animal… CONTINUE READING

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