Effects of amphetamine, morphine and dizocilpine (MK-801) on spontaneous alternation in the 8-arm radial maze

@article{Hlter1996EffectsOA,
  title={Effects of amphetamine, morphine and dizocilpine (MK-801) on spontaneous alternation in the 8-arm radial maze},
  author={Sabine M H{\"o}lter and Thomas M. Tzschentke and Werner J. Schmidt},
  journal={Behavioural Brain Research},
  year={1996},
  volume={81},
  pages={53-59}
}
  • Sabine M Hölter, Thomas M. Tzschentke, Werner J. Schmidt
  • Published in Behavioural Brain Research 1996
  • Psychology, Medicine
  • The induction of psychomotor activation, behavioural sensitization and of perseverative behaviours, resulting in reduced behavioural variability, have been proposed to be common properties of drugs of abuse. The present investigation tested whether these drug effects could be measured using spontaneous alternation in an 8-arm radial maze. Behavioural effects of repeated treatment with amphetamine (2 and 4 mg/kg, i.p.), morphine (1.25 and 10 mg/kg, i.p.) and the non-competitive NMDA receptor… CONTINUE READING

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