Effects of aminohydroxybutane bisphosphonate on bone growth when administered after hind-limb bone loss in tail-suspended rats.

@article{Apseloff1993EffectsOA,
  title={Effects of aminohydroxybutane bisphosphonate on bone growth when administered after hind-limb bone loss in tail-suspended rats.},
  author={Glen Apseloff and Beverly Girten and Steven E. Weisbrode and Michael F. Walker and L. S. Stern and M E Krecic and Nicholas Gerber},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1993},
  volume={267 1},
  pages={515-21}
}
The effects of aminohydroxybutane bisphosphonate (AHBuBP) on bone after disuse osteopenia were studied in tail-suspended rats. Male Sprague-Dawley rats (weight range, 313-352 g) randomized into four groups of eight animals received 2 ml kg-1 day-1 of either AHBuBP (0.3 mg kg-1 day-1) or normal saline (vehicle) subcutaneously on days 14 and 15 of a 28-day… CONTINUE READING