Effects of amino acid substitutions in and around the arginine-glycine-aspartic acid (RGD) sequence on fertilization and parthenogenetic development in mature bovine oocytes.

@article{Sessions2006EffectsOA,
  title={Effects of amino acid substitutions in and around the arginine-glycine-aspartic acid (RGD) sequence on fertilization and parthenogenetic development in mature bovine oocytes.},
  author={Benjamin R Sessions and Kenneth I. Aston and Anthony P Davis and Barry J Pate and Kenneth L. White},
  journal={Molecular reproduction and development},
  year={2006},
  volume={73 5},
  pages={651-7}
}
Integrins have been shown to be involved in the process of fertilization and many integrin-ligand interactions are mediated through the recognition of an arginine-glycine-aspartic acid (RGD) sequence. Despite the fact the RGD domain is a principal player in determining the functional characteristics of an adhesive protein, increasing evidence has accumulated implicating the amino acids flanking the RGD sequence in determining the functional properties of the RGD-containing protein. A set of… CONTINUE READING

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