Effects of altitude on endogenous carboxyhemoglobin levels.

  title={Effects of altitude on endogenous carboxyhemoglobin levels.},
  author={James J. McGrath},
  journal={Journal of toxicology and environmental health},
  volume={35 2},
  • James J. McGrath
  • Published 1992 in Journal of toxicology and environmental health
The effects of carbon monoxide (CO) on blood carboxyhemoglobin (COHb) levels, though well studied at sea level, have not been investigated in populations at altitude. COHb levels were measured in laboratory rats following 6 wk exposure to either clean air or air containing 9 ppm CO at ambient altitude (3300 ft), 10,000 ft, or 15,000 ft simulated high altitude. In animals breathing clean air, COHb levels increased with increasing altitude from 0.68 +/- 0.09% at 3300 ft to 1.16 +/- 0.28% and 1.68… CONTINUE READING