Effects of altered cardiac membrane fluidity on beta-adrenergic receptor signalling in rats with cirrhotic cardiomyopathy.

@article{Ma1997EffectsOA,
  title={Effects of altered cardiac membrane fluidity on beta-adrenergic receptor signalling in rats with cirrhotic cardiomyopathy.},
  author={Z Ma and Samuel Sangkon Lee and Jonathan B. Meddings},
  journal={Journal of hepatology},
  year={1997},
  volume={26 4},
  pages={904-12}
}
BACKGROUND/AIMS The relationship between cardiac plasma membrane physical properties and beta-adrenergic receptor signalling function in cirrhotic cardiomyopathy remains unclear. We aimed to clarify this issue by examining the effect of altering membrane fluidity on beta-adrenergic receptor signalling in cirrhotic rats. METHODS Cirrhosis was induced by chronic bile duct ligation, while controls were sham-operated. Left ventricular papillary muscle contractility was measured in an organ bath… CONTINUE READING

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