Effects of alterations in bolus viscosity on esophageal peristalsis in humans.

@article{Dooley1988EffectsOA,
  title={Effects of alterations in bolus viscosity on esophageal peristalsis in humans.},
  author={Chris Dooley and Brigitte Schlossmacher and Jorge E. Valenzuela},
  journal={The American journal of physiology},
  year={1988},
  volume={254 1 Pt 1},
  pages={G8-11}
}
The effect of increased bolus viscosity on esophageal peristaltic function was studied in six healthy volunteer subjects. Intraluminal pressure events were measured with an infused catheter system and lower esophageal sphincter pressure was monitored continuously with a Dent sleeve. Boluses with viscosities of 2.5, 8.7, 48, and 860 centipoise (cP) were compared with a water bolus. Increasing bolus viscosity to 48 and 860 cP elicited a slowing of wave velocity, an increase in wave duration, and… CONTINUE READING