Effects of alpha 1-acid glycoprotein in different rodent models of shock.

@article{Muchitsch1998EffectsOA,
  title={Effects of alpha 1-acid glycoprotein in different rodent models of shock.},
  author={Eva M. Muchitsch and Wilfried Auer and Ludwig Pichler},
  journal={Fundamental & clinical pharmacology},
  year={1998},
  volume={12 2},
  pages={
          173-81
        }
}
It was the aim of the present study to investigate the effects of the acute phase protein alpha 1-acid glycoprotein in different models of shock. The human plasma preparation used was without effect on mortality in lipopolysaccharide-injected mice when administered in two different doses (1 or 0.33 g/kg i.v.) and according to different treatment schedules. The same preparation significantly increased survival rate (48 h) in rats with septic peritonitis. This effect was seen when alpha 1-acid… CONTINUE READING

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