Effects of allergic diseases and age on the composition of serum IgG glycome in children

@inproceedings{Pezer2016EffectsOA,
  title={Effects of allergic diseases and age on the composition of serum IgG glycome in children},
  author={Marija Pezer and Jerko {\vS}tambuk and Marija Perica and Genadij Razdorov and Ivana Banic and Frano Vu{\vc}kovi{\'c} and Adrijana Miletic Gospic and Ivo Ugrina and Ana Vecenaj and Maja Pu{\vc}i{\'c} Bakovi{\'c} and Sandra Bulat Lokas and Jelena Zivkovic and Davor Plavec and Graham Devereux and Mirjana Turkalj and Gordan Lauc},
  booktitle={Scientific reports},
  year={2016}
}
It is speculated that immunoglobulin G (IgG) plays a regulatory role in allergic reactions. The glycans on the Fc region are known to affect IgG effector functions, thereby possibly having a role in IgG modulation of allergic response. This is the first study investigating patients' IgG glycosylation profile in allergic diseases. Subclass specific IgG glycosylation profile was analyzed in two cohorts of allergen sensitized and non-sensitized 3- to 11-year-old children (conducted at University… CONTINUE READING
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