Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.

@article{Belloni1987EffectsOA,
  title={Effects of alkylxanthines and calcium antagonists on adenosine uptake by cultured rabbit coronary microvascular endothelium.},
  author={F. Belloni and B. C. Liang and M. Gerritsen},
  journal={Pharmacology},
  year={1987},
  volume={35 1},
  pages={
          1-15
        }
}
  • F. Belloni, B. C. Liang, M. Gerritsen
  • Published 1987
  • Chemistry, Medicine
  • Pharmacology
  • Adenosine uptake by cultured rabbit coronary microvascular endothelial cells was studied. Radiolabeled [2-3H]-adenosine, present initially in the extracellular space at 10(-6) mol/l, was incorporated into the cell cultures at a steady rate during 30 s-3 h incubations. Incorporated 3H was found mostly (83%) in adenine nucleotides. Incorporation of [3H]-adenosine was attenuated by an adenosine deaminase inhibitor (EHNA) but only at adenosine concentrations of 10(-5) mol/l or higher. Adenosine… CONTINUE READING
    14 Citations
    Erythrocyte adenosine transport. A rapid screening test for cardiovascular drugs.
    • 13
    Influence of adenosine receptor blockade on renal function and renal autoregulation.
    • 27
    The Pharmacology of Adenosine
    • 82
    Exercise hemodynamic and neurohormone responses as sensitive biomarkers for diltiazem in rats.
    • P. Yeung, J. Feng,, D. Fice
    • Medicine
    • Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques
    • 2006
    • 2
    • PDF
    Pharmacologic profile of ropinirole
    • 67