Effects of alexidine.2HCL mouthwash on plaque and gingivitis after six months.

Abstract

Two-hundred and fourteen subjects ranging in age from 22 to 63 years used either a mouthwash that contained 0.035% w/v alexidine.2HCL (2-ethylhexyl bisbiguanidine dihydrochloride) or a placebo twice daily on a doubleblind basis for six months in conjunction with routine oral hygiene procedures. The results indicated that alexidine.2HCL was safe and was statistically more effective in producing a clinically significant reduction in gingivitis than was the placebo.

Cite this paper

@article{Spolsky1977EffectsOA, title={Effects of alexidine.2HCL mouthwash on plaque and gingivitis after six months.}, author={Vladimir W. Spolsky and Alan B. Forsythe}, journal={Journal of dental research}, year={1977}, volume={56 11}, pages={1349-58} }