Effects of alcohols on lipid bilayers with and without cholesterol: the dipalmitoylphosphatidylcholine system.

@article{Rosser1999EffectsOA,
  title={Effects of alcohols on lipid bilayers with and without cholesterol: the dipalmitoylphosphatidylcholine system.},
  author={Meredith F. N. Rosser and Hongbin Lu and Phoebe Dea},
  journal={Biophysical chemistry},
  year={1999},
  volume={81 1},
  pages={33-44}
}
Differential scanning calorimetry is a useful method to study the thermotropic phase transitions of a phospholipid bilayer. In the present study DSC is used to determine the effects of methanol and ethanol on DPPC and DPPC/2 mol% cholesterol bilayers. The biphasic effect of the main transition and the presence of an extra peak on the DSC cooling scans were observed above certain alcohol concentrations. In the presence of 2% cholesterol, the concentration at which the biphasic effect occurs is… CONTINUE READING