Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats.

@article{Yu2003EffectsOA,
  title={Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats.},
  author={C Yu and Carolyn A. Fairbanks and George L. Wilcox and Robert Yezierski},
  journal={The journal of pain : official journal of the American Pain Society},
  year={2003},
  volume={4 3},
  pages={129-40}
}
Intraspinal injection of the AMPA/metabotropic receptor agonist quisqualic acid (QUIS) results in a pathophysiology that leads to excessive grooming behavior, which has been proposed as a model of spontaneous at-level pain after spinal cord injury (SCI). To further characterize the onset and progression of this behavior we evaluated the effects of 3 drugs, agmatine (Agm), interleukin-10 (IL-10), and cyclosporin A (CsA), on different characteristics of this behavior. In these experiments rats… CONTINUE READING

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