Effects of aging on the work output and efficiency of rat papillary muscle.

@article{Kiriazis2000EffectsOA,
  title={Effects of aging on the work output and efficiency of rat papillary muscle.},
  author={Helen Kiriazis and Colin L. Gibbs},
  journal={Cardiovascular research},
  year={2000},
  volume={48 1},
  pages={
          111-9
        }
}
OBJECTIVES This study aimed to investigate the effect of aging on the work output and efficiency of rat papillary muscle. METHODS The mechanical and energetic properties of left ventricular papillary muscle preparations isolated from 6-, 15-, and 27- to 32-month-old Sprague-Dawley rats were measured in myothermic experiments at 27 degrees C at a stimulus frequency of 0.167 Hz. RESULTS We found that the basal metabolism measured in quiescent papillary muscles was significantly reduced in the… CONTINUE READING
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