Effects of aging on slow-wave sleep dynamics and human spatial navigational memory consolidation.

@article{Varga2016EffectsOA,
  title={Effects of aging on slow-wave sleep dynamics and human spatial navigational memory consolidation.},
  author={Andrew Varga and Emma L Ducca and Akifumi Kishi and Esther Fischer and Ankit Parekh and Viachaslau Koushyk and Po Lai Yau and Tyler Gumb and David P Leibert and Margaret E Wohlleber and Omar E Burschtin and Antonio Convit and David M Rapoport and R. S. Osorio and Indu A Ayappa},
  journal={Neurobiology of aging},
  year={2016},
  volume={42},
  pages={142-149}
}
The consolidation of spatial navigational memory during sleep is supported by electrophysiological and behavioral evidence. The features of sleep that mediate this ability may change with aging, as percentage of slow-wave sleep is canonically thought to decrease with age, and slow waves are thought to help orchestrate hippocampal-neocortical dialog that supports systems level consolidation. In this study, groups of younger and older subjects performed timed trials before and after… CONTINUE READING