Effects of aging on male fertility?

@article{Plas2000EffectsOA,
  title={Effects of aging on male fertility?},
  author={Eugen G. Plas and Peter Berger and Martin Hermann and Heinz Pfl{\"u}ger},
  journal={Experimental Gerontology},
  year={2000},
  volume={35},
  pages={543-551}
}
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141 Citations
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141 Citations

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Aging and the Male Gonads
TLDR
Various agerelated effects on Sertoli cells and Leydig cells are seen, with subsequent effects on the production of sperm and testosterone, and the effects of aging on testes are outlined.
Aging of the Male Germline: Influence of Advanced Male Age on ReproductiveOutcome
TLDR
Setting an age threshold for APA would be of great value to males thinking of delaying parenthood, and to physicians for medical advice purposes, and additional research to better elucidate the effects of APA on fertility and offspring’s health is needed.
Fertility and ageing.
TLDR
The late 20th century trend to delay birth of the first child until the age at which female fecundity or reproductive capacity is lower has increased the incidence of age-related infertility and stimulated interest in the possible factors in the female and the male that may contribute to the decline in fecundities with age.
The ageing male reproductive tract
TLDR
This review discusses morphological/histological changes occurring in these organs and current views and concepts of the underlying pathology, and emphasizes the molecular/cellular pathways leading to reduced testicular/penile function and proliferative disorders of the prostate gland.
Aging and male reproductive function: a mitochondrial perspective.
TLDR
Evidence is reviewed that suggests that mitochondria constitute a common link between aging and fertility loss, and that these organelles play a prominent role in this process.
Aging of the human ovary and testis
Fonctions testiculaires du sujet âgé
Consistent age-dependent declines in human semen quality: A systematic review and meta-analysis
Common Male Infertility Disorders: Aging
TLDR
The effects of paternal age on a couple’s fertility are real and may be greater than has previously been thought, and Mechanisms of cell senescence have been well studied in the last decade, and the free radical theory has brought considerable attention.
Hormonal Changes in Ageing Men
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TLDR
It is concluded that sperm counts and fertilizing capacity of sperm are not negatively influenced by old age, at least not in men with sustained sexual activity, however, the pituitary as well as the testis show signs of decreased endocrine reserve capacity in old age.
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TLDR
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