Effects of age on the gastroesophageal junction, esophageal motility, and reflux disease.

@article{Lee2007EffectsOA,
  title={Effects of age on the gastroesophageal junction, esophageal motility, and reflux disease.},
  author={Jacqueline C Lee and Angela Anggiansah and Roy Anggiansah and Alasdair R. Young and Terry Wong and Mark Fox},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2007},
  volume={5 12},
  pages={1392-8}
}
BACKGROUND & AIMS The prevalence of complicated gastroesophageal reflux disease (GERD) increases with age; however, the mechanism by which this occurs is uncertain. This study assessed (1) whether physiologic degradation of the gastroesophageal junction and esophageal motility occurs with aging, and (2) whether these effects are associated with increased esophageal acid exposure and reflux symptoms in the elderly. METHODS Retrospective study of 1307 patients referred for investigations of… CONTINUE READING

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