Effects of age and coronary artery disease on cerebrovascular reactivity to carbon dioxide in humans.

@article{Galvin2010EffectsOA,
  title={Effects of age and coronary artery disease on cerebrovascular reactivity to carbon dioxide in humans.},
  author={Sean D Galvin and Leo Anthony Celi and Kate Nicole Thomas and T R Clendon and Ivor F. Galvin and Richard W. Bunton and Philip N. Ainslie},
  journal={Anaesthesia and intensive care},
  year={2010},
  volume={38 4},
  pages={
          710-7
        }
}
Alterations in cerebrovascular reactivity to CO2, an index of cerebrovascular function, have been associated with increased risk of stroke. We hypothesised that cerebrovascular reactivity is impaired with increasing age and in patients with symptomatic coronary artery disease (CAD). Cerebrovascular and cardiovascular reactivity to CO2 was assessed at rest and during hypercapnia (5% CO2) and hypocapnia (hyperventilation) in subjects with symptomatic CAD (n=13) and age-matched old (n=9) and young… CONTINUE READING

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