Effects of afterload reduction on global left ventricular and regional myocardial functions in the isolated canine heart with stenosis of a coronary arterial branch.

@article{Isoyama1983EffectsOA,
  title={Effects of afterload reduction on global left ventricular and regional myocardial functions in the isolated canine heart with stenosis of a coronary arterial branch.},
  author={Shogen Isoyama and Yukio Maruyama and Kazuhiro Ashikawa and Sunao Sato and Hideaki Suzuki and Jun Watanabe and Yutaka Shimizu and E Ino-oka and Tamotsu Takishima},
  journal={Circulation},
  year={1983},
  volume={67 1},
  pages={139-47}
}
We examined the effects of graded reduction of afterload on the global left ventricular and regional myocardial functions as well as coronary hemodynamics in hearts with regional ischemia. We used isolated, paced canine hearts that were loaded with a hydraulic system that simulated the aortic input impedance of the dog's arterial tree. The loading… CONTINUE READING