Effects of advanced glycation end products on renal fibrosis and oxidative stress in cultured NRK-49F cells.

@article{Yan2007EffectsOA,
  title={Effects of advanced glycation end products on renal fibrosis and oxidative stress in cultured NRK-49F cells.},
  author={H. Yan and X. Li and Jun-mei Xie and M. Li},
  journal={Chinese medical journal},
  year={2007},
  volume={120 9},
  pages={
          787-93
        }
}
  • H. Yan, X. Li, +1 author M. Li
  • Published 2007
  • Chemistry, Medicine
  • Chinese medical journal
  • BACKGROUND Advanced glycation end products (AGEs) play a critical role in the development of diabetic nephropathy. Reactive oxygen species (ROS) may play a critical role in AGEs induced growth factor expression. In this study, the effects of AGEs on transforming growth factor beta1 (TGF-beta1), connective tissue growth factor (CTGF) and fibronectin (Fn) mRNA expression and oxidative stress in cultured NRK-49F cells were examined. METHODS NRK-49F cells were incubated with medium containing… CONTINUE READING
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