Effects of advanced glycation end products on renal fibrosis and oxidative stress in cultured NRK-49F cells.
@article{Yan2007EffectsOA, title={Effects of advanced glycation end products on renal fibrosis and oxidative stress in cultured NRK-49F cells.}, author={H. Yan and X. Li and Jun-mei Xie and M. Li}, journal={Chinese medical journal}, year={2007}, volume={120 9}, pages={ 787-93 } }
BACKGROUND
Advanced glycation end products (AGEs) play a critical role in the development of diabetic nephropathy. Reactive oxygen species (ROS) may play a critical role in AGEs induced growth factor expression. In this study, the effects of AGEs on transforming growth factor beta1 (TGF-beta1), connective tissue growth factor (CTGF) and fibronectin (Fn) mRNA expression and oxidative stress in cultured NRK-49F cells were examined.
METHODS
NRK-49F cells were incubated with medium containing… CONTINUE READING
Topics from this paper
48 Citations
6-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts
- Chemistry, Medicine
- Molecules
- 2019
- 3
- PDF
Cell signaling and receptors in toxicity of advanced glycation end products (AGEs): α-dicarbonyls, radicals, oxidative stress and antioxidants
- Chemistry, Medicine
- Journal of receptor and signal transduction research
- 2011
- 23
Induction of renal damage and modulation of redox potential in rats infused with glyoxal
- Chemistry
- 2012
- 4
Oxidative Stress and Advanced Lipoxidation and Glycation End Products (ALEs and AGEs) in Aging and Age-Related Diseases
- Chemistry, Medicine
- Oxidative medicine and cellular longevity
- 2019
- 51
- PDF
The effects of grape seed on apoptosis-related gene expression and oxidative stress in streptozotocin-induced diabetic rats
- Medicine
- Renal failure
- 2015
- 8
Advanced Glycation Endproducts Stimulate Renal Epithelial Cells to Release Chemokines That Recruit Macrophages, Leading to Renal Fibrosis
- Medicine
- Bioscience, biotechnology, and biochemistry
- 2012
- 9
Renal damage following Alloxan‐induced diabetes is associated with generation of reactive oxygen species, alterations of p53, TGF‐β1, and extracellular matrix metalloproteinases in rats
- Chemistry, Medicine
- Cell biology international
- 2017
- 4
Prophylactic role of arjunolic acid in response to streptozotocin mediated diabetic renal injury: activation of polyol pathway and oxidative stress responsive signaling cascades.
- Chemistry, Medicine
- Chemico-biological interactions
- 2009
- 54
Effect of coenzyme Q10 alone and its combination with metformin on streptozotocin-nicotinamide-induced diabetic nephropathy in rats
- Medicine
- Indian journal of pharmacology
- 2014
- 31