Effects of adult-onset choline deprivation on the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase in crucial rat brain regions.

@article{Liapi2009EffectsOA,
  title={Effects of adult-onset choline deprivation on the activities of acetylcholinesterase, (Na+,K+)- and Mg2+-ATPase in crucial rat brain regions.},
  author={Charis Liapi and Argyro Kyriakaki and Apostolos Ch Zarros and Hussam Al-Humadi and Vasileios Stolakis and Elena Gkrouzman and Foteini Anifantaki and Nikolina Skandali and Marios Margaritis and Stylianos Th Tsakiris},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2009},
  volume={47 1},
  pages={82-5}
}
Choline (Ch) plays an important role in brain neurotransmission, while Ch-deprivation (CD) has been linked to various pathophysiological states. Prolonged ingestion of Ch-deficient diet (CDD) is known to produce CD causing a reduction of rat brain acetylcholine (ACh) levels, as well as memory and growth disorders. The aim of this study was to investigate the effect of a 2-month adult-onset CD on the activities of acetylcholinesterase (AChE), (Na+,K+)- and Mg2+-ATPase in crucial brain regions of… CONTINUE READING