Effects of adrenaline and hyaluronidase on plasma concentrations of lignocaine and bupivacaine after peribulbar anaesthesia.

@article{Barr1995EffectsOA,
  title={Effects of adrenaline and hyaluronidase on plasma concentrations of lignocaine and bupivacaine after peribulbar anaesthesia.},
  author={Joseph Martin Barr and Niall Kirkpatrick and Arthur L. Dick and Llewellyn. Leonard and Gabrielle H Hawksworth and David W. Noble},
  journal={British journal of anaesthesia},
  year={1995},
  volume={75 6},
  pages={
          692-7
        }
}
We have measured peak plasma concentrations of lignocaine and bupivacaine after dual injection peribulbar block and investigated the influence of adrenaline and hyaluronidase. Twenty-four patients were allocated randomly to one of four groups: (I) local anaesthetic alone (lignocaine 10 mg ml-1-bupivacaine 3.75 mg ml-1); (II) local anaesthetic with adrenaline (5 micrograms ml-1); (III) local anaesthetic with hyaluronidase (75 iu ml-1); or (IV) local anaesthetic with adrenaline and hyaluronidase… CONTINUE READING
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