Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice.

@article{Camarini2008EffectsOA,
  title={Effects of adolescent exposure to cocaine on locomotor activity and extracellular dopamine and glutamate levels in nucleus accumbens of DBA/2J mice.},
  author={Rosana Camarini and William C Griffin and Amy B. Yanke and Benvinda Rosalina dos Santos and M Foster Olive},
  journal={Brain research},
  year={2008},
  volume={1193},
  pages={34-42}
}
Adolescents differ from adults in their acute sensitivity to several drugs of abuse, but little is known about the long-term neurobehavioral effects of adolescent drug exposure. To explore this further, we evaluated the locomotor responses to repeated cocaine administration in adolescent and adult male DBA/2J mice and alterations in extracellular levels of dopamine (DA) and glutamate (GLU) in the nucleus accumbens (NAc) in response to a subsequent cocaine challenge. Adolescent and adult mice… CONTINUE READING
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