Effects of adolescent ethanol exposure on event-related oscillations (EROs) in the hippocampus of adult rats

  title={Effects of adolescent ethanol exposure on event-related oscillations (EROs) in the hippocampus of adult rats},
  author={Jos{\'e} R Criado and Cindy L. Ehlers},
  journal={Behavioural Brain Research},

Figures from this paper

Event-related potential responses to the acute and chronic effects of alcohol in adolescent and adult Wistar rats.
Adolescent rats have a less intense P3 latency response to acute EtOH administration when compared to adult rats, and exposure to chronic EtOH during adolescence can cause "retention" of the adolescent phenotype of reduced P 3 latency sensitivity to EtOH.
Prolonged chronic ethanol exposure alters neuropeptide Y and corticotropin-releasing factor levels in the brain of adult Wistar rats
Decreases in Energy and Increases in Phase Locking of Event-Related Oscillations to Auditory Stimuli Occur during Adolescence in Human and Rodent Brain
Findings are consistent with the hypothesis that adolescent remodeling of the brain includes decreases in energy and increases in synchrony over a wide frequency range both within and between neuronal networks and that these effects are conserved over evolution.
PSPH-D-18-00526: Effect of a dual orexin receptor antagonist (DORA-12) on sleep and event-related oscillations in rats exposed to ethanol vapor during adolescence
It is shown that DORA-12 can affect the sleep disturbance that is associated with a history of adolescent ethanol exposure and also has several other sleep-promoting effects that are equivalent in both ethanol and control rats.
Local and regional network function in behaviorally relevant cortical circuits of adult mice following postnatal alcohol exposure.
The results suggest that both the activity of local neural circuits within a brain region and the flow of information between brain regions can be modified by early alcohol exposure, which may contribute to long-lasting behavioral abnormalities known to rely on those circuits.


Altered EEG responses to ethanol in adult rats exposed to ethanol during adolescence.
  • C. Slawecki
  • Medicine
    Alcoholism, clinical and experimental research
  • 2002
Investigation of long-term changes in EEG activity after EtOH challenge in adult rats exposed to EtOH during adolescence suggests that adolescent ethanol exposure produces long-lasting tolerance to the sedative effects of ethanol.
Effects of adolescent ethanol exposure on sleep in adult rats.
Electrophysiological effects of dizocilpine (MK-801) in adult rats exposed to ethanol during adolescence.
The effects of MK-801 on hippocampal EEG variability and P3 ERP amplitude and latency are significantly attenuated after a prolonged withdrawal period following adolescent EtOH exposure, and the inhibitory effects of the NMDA antagonist on cortical and hippocampus EEG power were enhanced in rats exposed to EtOH during adolescence.
Periadolescent alcohol exposure has lasting effects on adult neurophysiological function in rats.
Neurobehavioral profiles during the acute phase of ethanol withdrawal in adolescent and adult Sprague-Dawley rats
EEG and ERP response to chronic ethanol exposure in rats
Chronic ethanol exposure has been described in humans to produce a series of long and short term electrophysiological consequences. Interpretation of the electrophysiological findings in human
Effects of chronic ethanol exposure on neurophysiological responses to corticotropin-releasing factor and neuropeptide Y.
Enhanced sensitivity to CRF and NPY following chronic ethanol exposure and abstinence suggests that these peptidergic systems may play a role in the symptomatology of the prolonged abstinence syndrome.
Adolescent alcohol drinking and its long-range consequences. Studies with animal models.
The findings indicate that P rats readily initiate alcohol drinking during the early post-weaning, adolescent and peri-adolescent periods of development, and produces long-lasting effects that increase the acquisition of ethanol self-administration in adulthood, and increase craving-like behavior and the potential for alcohol relapse.
Differential effects of ethanol in adolescent and adult rats.
Peri-adolescent rats are less sensitive to the sedative effects of ethanol as they recovered their righting reflex earlier and at significantly higher SECs than adult rats.