• DOI:10.1016/0028-3908(92)90157-K
Corpus ID: 21560651

Effects of adinazolam on plasma catecholamine, heart rate and blood pressure responses in stressed and non-stressed rats

@article{Krieman1992EffectsOA,
  title={Effects of adinazolam on plasma catecholamine, heart rate and blood pressure responses in stressed and non-stressed rats},
  author={M. Krieman and D. Hershock and I. Greenberg and W. Vogel},
  journal={Neuropharmacology},
  year={1992},
  volume={31},
  pages={33-38}
}

M. Krieman, D. Hershock, +1 author W. Vogel

Published 1992

Medicine

Neuropharmacology

Adinazolam (ADI) is a new benzodiazepine with anxiolytic and antidepressant properties. To assess its effects on the acute stress response, rats were given a single intraperitoneal injection of 2.5 or 5.0 mg/kg of ADI and stressed for 1 hr by restraint. Neither dose of ADI had any effect on heart rate, blood pressure or norepinephrine (NE) and epinephrine (EP) in plasma in the resting rats. In the stressed animal, 2.5 and 5.0 mg/kg of ADI did not affect stress-induced increases in heart rate or… CONTINUE READING

View on Elsevier

doi.org

Save to Library

Create Alert

Cite

Launch Research Feed