Effects of adenosine on liver cell damage induced by carbon tetrachloride.

  title={Effects of adenosine on liver cell damage induced by carbon tetrachloride.},
  author={Rolando Hern{\'a}ndez-Mu{\~n}oz and W Glender and M D{\'i}az M{\'u}{\~n}oz and J. Adolfo and Jes{\'u}s Adolfo Garc{\'i}a-S{\'a}inz and Victoria Chagoya de S{\'a}nchez},
  journal={Biochemical pharmacology},
  volume={33 16},
Adenosine administration delayed the fatty liver and cell necrosis induced by carbon tetrachloride without affecting the action of the hepatotoxin on protein synthesis and liver triacylglycerol release. Adenosine produced a drastic antilipolytic effect accompanied by a decrease in the incorporation of [1-14C]palmitic acid into triacylglycerols and free fatty acids of the liver. Furthermore, a decrease in the serum levels of ketone bodies was observed at early times. The nucleoside also avoided… CONTINUE READING
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