Effects of adding cognitive therapy to fluoxetine dose increase on risk of relapse and residual depressive symptoms in continuation treatment of major depressive disorder.

@article{Perlis2002EffectsOA,
  title={Effects of adding cognitive therapy to fluoxetine dose increase on risk of relapse and residual depressive symptoms in continuation treatment of major depressive disorder.},
  author={Roy H. Perlis and Andrew Nierenberg and Jonathan E. Alpert and Joel A. Pava and John D. Matthews and Jaqueline Buchin and Andrea H Sickinger and Maurizio Fava},
  journal={Journal of clinical psychopharmacology},
  year={2002},
  volume={22 5},
  pages={474-80}
}
Patients with major depressive disorder remain at risk for relapse following remission and often continue to experience subthreshold symptoms. This study compared the rate of relapse of major depressive disorder and the prevalence of residual depressive symptoms during the continuation phase for patients treated with fluoxetine dose increase alone or in combination with cognitive therapy. A total of 132 outpatients with major depressive disorder who achieved remission with 8 weeks of treatment… CONTINUE READING

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