Effects of acute ultra-low dose mecamylamine on cognition in adult attention-deficit/hyperactivity disorder (ADHD).

@article{Potter2009EffectsOA,
  title={Effects of acute ultra-low dose mecamylamine on cognition in adult attention-deficit/hyperactivity disorder (ADHD).},
  author={Alexandra S. Potter and Katherine K. Ryan and Paul A. Newhouse},
  journal={Human psychopharmacology},
  year={2009},
  volume={24 4},
  pages={309-17}
}
OBJECTIVE Nicotinic cholinergic stimulation has known beneficial effects in attention-deficit/hyperactivity disorder (ADHD). Mecamylamine is a non-competitive nicotinic antagonist which is reported in several animal studies to have paradoxical positive effects on cognition at ultra-low doses. Comparable studies in humans have not been conducted. The aim of this study was to determine the effects of acute ultra-low doses of mecamylamine on cognition in adult ADHD. METHODS Fifteen (6 female… CONTINUE READING
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