Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man.

@article{Tessari1991EffectsOA,
  title={Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man.},
  author={Paolo Tessari and S. Inchiostro and Gianni Biolo and Ezio Vincenti and L Sabadin},
  journal={The Journal of clinical investigation},
  year={1991},
  volume={88 1},
  pages={27-33}
}
To investigate the mechanism(s) of insulin-induced suppression of plasma amino acid concentration and release, we studied forearm as well as whole-body leucine and phenylalanine uptake and release during a peripheral insulin infusion in postabsorptive normal subjects using isotope-dilution methods. Before insulin, leucine and phenylalanine release exceeded uptake (P less than 0.01 and P less than 0.07, respectively). A net output of alpha-ketoisocaproate (KIC) was also observed. During insulin… CONTINUE READING
26 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…