Effects of acute ovarian hormone suppression on the human brain: an in vivo 1H MRS study.

@article{Craig2007EffectsOA,
  title={Effects of acute ovarian hormone suppression on the human brain: an in vivo 1H MRS study.},
  author={Michael C. Craig and Eileen M. Daly and Ruth Tuura O'Gorman and Janice Rymer and David J. Lythgoe and Ginny Ng and Andrew Simmons and Pauline M. Maki and Declan Murphy},
  journal={Psychoneuroendocrinology},
  year={2007},
  volume={32 8-10},
  pages={1128-32}
}
A previous proton magnetic resonance spectroscopy ((1)H MRS) study carried out by our group indicated that post-menopausal women who started taking oestrogen therapy (ET) at or around the menopause had a significantly lower choline (Cho) concentration in the hippocampus and parietal lobe than those who were ET naïve, suggesting that long-term ET positively modulates neuronal/glial membrane turnover in older females. The objective of the current study was to determine whether neuronal membrane… CONTINUE READING