Effects of acute or chronic exposure to dietary organic anions on secretion of methotrexate and salicylate by Malpighian tubules of Drosophila melanogaster larvae.

@article{Chahine2010EffectsOA,
  title={Effects of acute or chronic exposure to dietary organic anions on secretion of methotrexate and salicylate by Malpighian tubules of Drosophila melanogaster larvae.},
  author={Sarah Chahine and M. O'Donnell},
  journal={Archives of insect biochemistry and physiology},
  year={2010},
  volume={73 3},
  pages={
          128-47
        }
}
  • Sarah Chahine, M. O'Donnell
  • Published 2010
  • Medicine, Biology
  • Archives of insect biochemistry and physiology
  • The effects of dietary exposure to organic anions on the physiology of isolated Malpighian tubules and on tubule gene expression were examined using larvae of Drosophila melanogaster. Acute (24 h) or chronic (7 d) exposure to type I organic anions (fluorescein or salicylate) was associated with increased fluid secretion rates and increased fluxes of both salicylate and the type II organic anion methotrexate. By contrast, chronic exposure to dietary methotrexate was associated with increased… CONTINUE READING
    Interactions between detoxification mechanisms and excretion in Malpighian tubules of Drosophila melanogaster
    • 62
    • Open Access
    Osmoregulation and excretion.
    • 110
    • Open Access
    Oatp58Dc contributes to blood-brain barrier function by excluding organic anions from the Drosophila brain.
    • 10
    • Open Access

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 26 REFERENCES
    Novel aspects of the transport of organic anions by the malpighian tubules of Drosophila melanogaster.
    • 45
    • Open Access
    The effects of CO2 and external buffering on ammonia excretion and Rhesus glycoprotein mRNA expression in rainbow trout
    • 54
    • Open Access
    Using FlyAtlas to identify better Drosophila melanogaster models of human disease
    • 1,347
    Somatic mutation and recombination test in Drosophila melanogaster.
    • 585