Effects of acute dopamine-agonist treatment in restless legs syndrome on heart rate variability during sleep.

@article{Manconi2011EffectsOA,
  title={Effects of acute dopamine-agonist treatment in restless legs syndrome on heart rate variability during sleep.},
  author={M. Manconi and R. Ferri and M. Zucconi and S. Clemens and F. Rundo and A. Oldani and L. Ferini-Strambi},
  journal={Sleep medicine},
  year={2011},
  volume={12 1},
  pages={
          47-55
        }
}
OBJECTIVE To compare heart rate variability (HRV) changes in patients with restless legs syndrome (RLS) and in healthy subjects, and to evaluate HRV before and after treatment with pramipexole in RLS patients. METHODS A prospective, polysomnographic, single-blind, placebo-controlled study was performed in 23 patients with RLS and 10 healthy subjects. Basal spectral analysis of HRV and phasic heart rate (HR) changes during PLMS were compared between the two groups and, within the RLS group… Expand
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