Effects of acute detoxification of the herbal blend 'Spice Gold' on dopamine D2/3 receptor availability: a [18F]fallypride PET study.

@article{Rominger2013EffectsOA,
  title={Effects of acute detoxification of the herbal blend 'Spice Gold' on dopamine D2/3 receptor availability: a [18F]fallypride PET study.},
  author={Axel Rominger and Paul Cumming and Guoming Xiong and G. Koller and Stefan F{\"o}rster and Andreas Zwergal and Evangelos T. Karamatskos and Peter Bartenstein and Christian la Foug{\'e}re and Oliver Pogarell},
  journal={European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year={2013},
  volume={23 11},
  pages={1606-10}
}
We carried out dynamic [(18)F]fallypride PET scans to measure cerebral dopamine D2/3 receptor availability in a 23-year old patient experiencing a severe withdrawal syndrome upon voluntary abstinence from "Spice", a pre-packaged herbal smoking thought to contain synthetic cannabinoids. Upon admission to the clinic, the patient experienced craving, affective symptoms and a range of somatic complaints, which resolved after several days' monitored abstinence. PET scans were performed on the day of… CONTINUE READING

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