Effects of acute and chronic treatment with amoxapine and cericlamine on the sleep-wakefulness cycle in the rat.

@article{Maudhuit1994EffectsOA,
  title={Effects of acute and chronic treatment with amoxapine and cericlamine on the sleep-wakefulness cycle in the rat.},
  author={Corinne Maudhuit and T. Jolas and Erik Lainey and Michel Hamon and Jo{\"e}lle Adrien},
  journal={Neuropharmacology},
  year={1994},
  volume={33 8},
  pages={1017-25}
}
Antidepressant drugs, such as the tricyclics and the serotonin reuptake inhibitors, are well known to decrease paradoxical sleep and occasionally increase slow wave sleep in human and in animals. In order to examine whether amoxapine (a mixed NA reuptake blocker and 5-HT2/5-HT3 antagonist) and cericlamine (a selective 5-HT reuptake inhibitor) exert the same effect in rats, and to investigate the possible relationships between sleep, the action of antidepressants and the serotoninergic system… CONTINUE READING