Effects of acute and chronic parathyroidectomy on phosphate transport in brush border membrane vesicles

@article{Hirano1989EffectsOA,
  title={Effects of acute and chronic parathyroidectomy on phosphate transport in brush border membrane vesicles},
  author={Kiyoshi Hirano and Masaki Nagasawa and M Kubota and Yasuhiko Tomino and Hikaru Koide},
  journal={Journal of Bone and Mineral Metabolism},
  year={1989},
  volume={7},
  pages={31-37}
}
Acute parathyroidectomy (PTX) is associated with an increase in phosphate (Pi) uptake by renal cortical brush border membrane (BBM). We investigated the response to acute and chronic PTX in the renal BBM. Kinetic studies of Pi uptake were carried out in 5 groups of rats as follows; control, acute PTX (1h), chronic PTX (20h and 72h), and chronic PTX (20h) treated with 10 IU of parathyroid hormone (PTH). The Na+-dependent Pi transport in BBMV was significantly increased 1h after PTX. However… CONTINUE READING

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