Effects of activin A on pancreatic ductal cells in streptozotocin-induced diabetic rats.


BACKGROUND The shortage of islets for transplantation has led to find alternative insulin producing cells. Pancreatic progenitor cells in the duct have the potential to grow and differentiate into endocrine cells. In this study, we examined whether activin A can promote the expansion and/or differentiation of ductal cells into insulin-producing cells… (More)