Effects of acetyl-l-carnitine on regional cerebral glucose metabolism in awake rats

@article{Ori2002EffectsOA,
  title={Effects of acetyl-l-carnitine on regional cerebral glucose metabolism in awake rats},
  author={Carlo Ori and Ulderico Freo and Gilberto Pizzolato and Mauro Dam},
  journal={Brain Research},
  year={2002},
  volume={951},
  pages={330-335}
}
The time-course and relation to dose of regional metabolic rates for glucose (rCMRglc) were measured in awake adult Fischer-344 rats after administration of acetyl-L-carnitine (ALCAR), an agent that modulates neuronal energy processes and neurotransmitter synthesis. rCMRglc were determined with the quantitative [(14)C]2-deoxy-D-glucose technique in 50 brain regions at 10, 30 and 60 min after i.v. administration of ALCAR 500 mg/kg and at 30 min after ALCAR 250 and 700 mg/kg or coadministration… CONTINUE READING
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