Effects of acclimation and incubation temperature on the glutathione antioxidant system in killifish and RTH-149 cells.

@article{Leggatt2007EffectsOA,
  title={Effects of acclimation and incubation temperature on the glutathione antioxidant system in killifish and RTH-149 cells.},
  author={Rosalind A Leggatt and Colin J Brauner and Patricia M Schulte and George K. Iwama},
  journal={Comparative biochemistry and physiology. Part A, Molecular & integrative physiology},
  year={2007},
  volume={146 3},
  pages={317-26}
}
Glutathione (GSH) is an important antioxidant that is involved in a multitude of cellular processes. However, in fish, GSH levels, turnover, and activity of associated enzymes are low when compared to those of mammals. To determine whether temperature influences the GSH antioxidant system in fish, and can explain the differences in GSH between fish and mammals, we examined the effects of acclimation temperature on total GSH (tGSH) levels and apparent half-life (as an estimate of turnover) in a… CONTINUE READING

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