Effects of a transfusion with a blood substitute (Fluosol-DA, 20%) on cerebral circulation in the monkey.

@article{Nagasawa1981EffectsOA,
  title={Effects of a transfusion with a blood substitute (Fluosol-DA, 20%) on cerebral circulation in the monkey.},
  author={Shiro Nagasawa and Hajime Handa and Yoshihiro Naruo and Yoshinao Oda and Yasuhiro Yonekawa and Y. Takebe},
  journal={Neurological research},
  year={1981},
  volume={3 3},
  pages={
          237-50
        }
}
Local cerebral blood flow (lCBF) and electroencephalogram were monitored in six monkeys after a transfusion using a perfluorochemical suspension (Fluosol-DA, 20%) that has been manufactured as a blood substitute and is known to be synthetic, biologically inert, and nontoxic and to have a high capacity for carrying oxygen. The animals were mechanically ventilated, and blood gases were maintained at physiological levels. Fluosol-DA, 20% was administered either by an exchange transfusion of 20 ml… CONTINUE READING