Effects of a stressor and corticotrophin releasing factor on ethanol deprivation-induced ethanol intake and anxiety-like behavior in alcohol-preferring P rats

@article{Knapp2011EffectsOA,
  title={Effects of a stressor and corticotrophin releasing factor on ethanol deprivation-induced ethanol intake and anxiety-like behavior in alcohol-preferring P rats},
  author={Darin J. Knapp and David H. Overstreet and Mae M Huang and Tiffany A. Wills and Buddy A. Whitman and Robert A. Angel and Sarah E. Sinnett and George R. Breese},
  journal={Psychopharmacology},
  year={2011},
  volume={218},
  pages={179-189}
}
Stress may elevate ethanol drinking and anxiety associated with ethanol drinking. Studies to identify relevant neurobiological substrates are needed. To assess roles of brain regions in corticotrophin releasing factor (CRF) effects on stressor-enhanced, ethanol deprivation-induced drinking and anxiety-like behavior. Ethanol-preferring rats (P rats) were exposed to three cycles of a two-bottle choice paradigm with two 2-day deprivation periods that included 1 h exposure to a restraint stressor… CONTINUE READING
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