Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis.

@article{Athanasiadis2008EffectsOA,
  title={Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis.},
  author={Theo Athanasiadis and Achim Beule and B. H. Robinson and Simon R Robinson and Z Shi and Peter John Wormald},
  journal={The Laryngoscope},
  year={2008},
  volume={118 6},
  pages={1088-94}
}
INTRODUCTION Postoperative bleeding and adhesion formation remain the two major problems after endoscopic sinus surgery (ESS). This study investigates the effect on adhesion formation and wound healing in a sheep model of chronic sinusitis of three topical agents: recombinant tissue factor (rTF, Dade Innovin, Marburg, Germany), poly-ethylene glycol (SprayGel, Confluent Surgical, Waltham, MA), and a novel chitosan-dextran derivative gel (CD, Department of Chemistry, University of Otago, Dunedin… CONTINUE READING
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