Effects of a novel arginine-vasopressin derivative, NC-1900, on the spatial memory impairment of rats with transient forebrain ischemia.

@article{Hori2002EffectsOA,
  title={Effects of a novel arginine-vasopressin derivative, NC-1900, on the spatial memory impairment of rats with transient forebrain ischemia.},
  author={Etsuro Hori and Teruko Uwano and Ryoko Tamura and Norihisa P. Miyake and Hisao Nishijo and Taketoshi Ono},
  journal={Brain research. Cognitive brain research},
  year={2002},
  volume={13 1},
  pages={
          1-15
        }
}
NC-1900, an arginine-vasopressin derivative, has been reported to enhance memory for avoidance behavior. Specifically, NC-1900 ameliorated cycloheximide-induced learning impairments in a passive avoidance test in rats. In the present study, we investigated that effects of NC-1900 on place learning in rats with selective lesions in the CA1 subfield of the hippocampal formation produced by transient forebrain ischemia. NC-1900 was administered daily (1 microg/kg, p.o.) 1 h before the place… CONTINUE READING

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